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Especially, tell your doctor if you take: other medicines for high blood terms pressure or a heart problem water pills (diuretics) potassium supplements. These doses in mice and rats are about.6 and 6 times, respectively, the mrhd on a mg/m basis. Drug Interactions Hydrochlorothiazide Drugs that alter payment gastrointestinal motility : The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden apparently due to terms a decrease in gastrointestinal motility and the stomach emptying rate. Consult your doctor before breastfeeding. Also in bile, ten metabolites were detected, which were formed through N- and O- demethylation, terms hydroxylation of desosamine and aglycone rings and cleavage of cladinose conjugate. 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